刚刚看到duke的研究，很高兴看到他们的研究数据初步显示对HSV2有效。
他们的研究可是真正能消灭HSV的哦~~。
What is the current status of your research?
Currently, we have completed our work on identifying small regulatory
microRNAs encoded by the genital herpes virus, HSV-2, and it turns out that
these are very similar to what we see in HSV-1 (oral herpes). So, a similar
treatment approach may succeed with both viruses. We are continuing our
efforts to test new “antisense” drugs in mice, and this work is moving
rather slowly at present, given the cost of animal experiments. However,
our initial data are promising. It will certainly still be years until we
have a drug candidate ready for clinical trial. I am sorry that we cannot
move faster, but am hopeful that a new grant proposal will be funded and
will allow us to proceed more rapidly.
We hope this information answers your questions and is helpful. Please be
assured that we are continuing to work on the problem of developing novel
HSV-1 and HSV-2 treatment approaches.
Sincerely,
Bryan R. Cullen
Jennifer Lin Umbach
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Bryan R. Cullen, Ph.D.
James B. Duke Professor
Department of Molecular Genetics and Microbiology
Director, Duke University Center for Virology
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