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布卢姆医生发送电子邮件至慧聪会员(Frizzle) [复制链接]

1#
Thank you for your email.感谢您的来信。 Sorry for my delay in getting back to you but I have been traveling.对不起,我又回到了你延迟,但我一直在旅行。 The answers to your questions are below:在回答您的问题是如下:

1. 1。 What progress has your team currently made in locating a cure for HSV?您的团队取得了哪些进展,目前在寻找一种单纯疱疹病毒治疗呢?

I use the term "cure" carefully.我用这个词“治疗”小心。 I think eliminating HSV from the body is a very difficult goal.我认为单纯疱疹病毒从体内消除是一个非常难以实现的目标。 Our aim is to generate a more effective meams of suppressing the virus so that it will not reactivate and coause clinical disease.我们的目标是抑制病毒产生一个更有效的meams,以便它不会恢复和coause临床疾病。 To that end we have recently demonstrated that our anti-HSV ribozymes are effective at blocking replication and reactivation of HSV-1 when applied topically.最近,我们已证明,我们的抗HSV核酶是在阻止复制和HSV - 1的激活有效结束时,适用于局部。

2. 2。 Do you believe it is possible to not only cure HSV1 but also HSV2?你相信这不仅是可能的,而且治疗单纯疱疹病毒HSV2?

Yes.是的。 Based on our success with HSV-1 we are currently testing anti-HSV-2 ribozymes for their effectiveness at blocking HSV-2 reactivation.基于我们与HSV - 1的成功,我们正在测试在封闭的HSV - 2活化抗HSV - 2核酶的有效性。

3. 3。 What obstacles do you and your team face in conducting further research?做什么障碍进行进一步的研究,你和你的团队的脸?

The toughest issue we face is obtaining funding for the remaining pre-clincal tests of our ribozymes.我们面临的最棘手的问题是获取剩余的前临床试验,我们核酶资金。 These tests are a pre-requisite for gaining approval to conduct human clinical trails.这些测试是一个预先获得批准进行人体临床试验的必要条件。

4. 4。 By when do you believe a cure can be marketed?到时你会相信治疗方法可以在市场上销售?

If our current research is successful and goes as planned I would estimate it would be 4 - 5 years before a product would hit the market.如果我们目前的研究是成功的,都照计划进行,我估计这将是4 - 5年之前,产品将投放市场。

5. 5。 How can a person donate to your cause in searching for a HSV cure?一个人如何能在您的事业捐赠了单纯疱疹病毒治疗搜索?

Donations for our research can be made to the folllowing acccounts:为我们的研究捐赠可向folllowing acccounts:

For HSV-1 ribozyme therapy:对于HSV - 1的核酶治疗:
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