昨天给American Social Health Association发了电子邮件，今天就收到了他们的回复，很详细，人家还真是很认真的。这两天很忙，下个星期把这篇文章给大家翻译一下，是关于疱疹与怀孕的相关问题，全文如下：
Thank you for contacting the HSVnet Email Response Service; we are glad to be of service to you. We are a program of the American Social Health Association, a non-profit organization, and are dedicated to educating people about oral and genital herpes.
First, let us reassure you that most women with genital herpes can have healthy, normal babies the regular way. It is rare for complications to arise during pregnancy because of herpes. Having an outbreak during pregnancy should not cause abortion or birth deformities.
Herpes does not affect conception of a child as a person's sexual fluids (such as semen and vaginal secretions) do not transmit the viru. Also, herpes is not present in the blood, so it is not usually transmitted from mother to child across the placenta. Herpes is transmitted through direct skin to skin contact. This occurs when a contagious area comes into contact with a mucous membrane, primarily the mouth and genitals.
While it is estimated one out of four women giving birth have genital herpes, less than 0.1% of babies actually contract the virus. Contrary to some misinformation and misconceptions, herpes rarely affects pregnancy. Still, if a woman has genital herpes, it is important that she discuss this with her health care provider. A thorough visual exam will need to be done at the onset of labor to ensure that there are no herpes lesions. If an outbreak is occurring, a c-section is typically performed; however, most women with genital herpes are able to deliver vaginally. It is important to stress that a c-section (because of herpes) is only recommended when symptoms are present during labor. Also, it is important to understand that a woman who has genital herpes has antibodies to the virus and passes these on to her baby during pregnancy, providing added protection during delivery. So a mother actually helps her baby during the pregnancy. The highest risk for herpes and pregnancy is when a woman contracts the virus for the very first time during the third trimester of pregnancy. In this situation, called a true primary outbreak, the mother does not have antibodies built up to the virus and has not been able to pass any to the infant. This type of situation is rare and does not always result in a baby contracting the virus.
In regards to your questions about acyclovir, none of the antiviral medications for herpes have been approved by the FDA for use during pregnancy because none have been studied in that capacity. However, Glaxo Wellcome (now GlaxoSmithKline) maintained a pregnancy registry between 1984 and 1999, where women taking either Zovirax (acyclovir) or Valtrex (valcyclovir) were tracked. Data collected from the registry showed no increased risk of birth defects for either of the medications. While this registry was designed for health care professionals, you may be able to find more information on it by contacting GlaxoSmithKline's Consumer Information Line at (888) 825-5249, 8:15am to 4:15pm, Eastern Time, Monday through Friday-- we are not sure if you can contact this number from China, though. Perhaps you might have better success trying to contact GlaxoSmithKline via email. Or, your health care provider may already have access to this information. As far as treatment during pregnancy, although it is generally desirable for a pregnant woman not to be taking medication during the early part of her pregnancy, some providers and researchers feel that taking one of the antiviral medications (acyclovir, valcyclovir, famciclovir) during the third trimester will help reduce the risk of transmission to an infant.
